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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
1.21
Human Site:
S601
Identified Species:
2.05
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S601
G
H
A
S
S
P
D
S
E
V
T
S
L
C
Q
Chimpanzee
Pan troglodytes
XP_509445
540
59236
E435
H
A
S
S
P
D
S
E
V
T
S
L
C
Q
K
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
A601
G
H
A
S
S
P
D
A
E
V
T
S
L
C
Q
Dog
Lupus familis
XP_534658
709
78944
D603
V
E
H
S
L
S
P
D
S
E
P
P
L
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
A603
P
E
P
S
C
S
P
A
A
G
A
A
V
L
S
Rat
Rattus norvegicus
NP_001099399
476
51796
P371
P
D
T
A
S
P
E
P
S
C
S
P
A
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
E610
L
Q
S
S
P
A
G
E
A
T
V
L
C
E
K
Chicken
Gallus gallus
Q5F3D1
613
68449
L508
V
P
E
N
E
H
S
L
T
S
P
N
P
D
N
Frog
Xenopus laevis
Q6DD45
743
82926
P638
E
E
G
G
P
L
I
P
E
E
D
S
E
T
N
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
D585
M
T
D
K
T
N
S
D
G
K
Q
E
I
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
T448
D
V
N
A
S
H
N
T
T
A
N
E
S
K
S
Honey Bee
Apis mellifera
XP_001122586
556
62911
L451
K
K
Q
L
L
V
E
L
Q
E
S
N
L
D
I
Nematode Worm
Caenorhab. elegans
P34656
453
51815
V348
L
T
P
I
R
K
D
V
K
L
G
E
S
M
F
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
E521
K
G
R
N
G
K
D
E
S
K
D
K
K
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
93.3
13.3
N.A.
6.6
13.3
N.A.
6.6
0
13.3
0
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
26.6
100
13.3
N.A.
26.6
40
N.A.
20
13.3
13.3
13.3
N.A.
26.6
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
15
0
8
0
15
15
8
8
8
8
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
15
15
8
% C
% Asp:
8
8
8
0
0
8
29
15
0
0
15
0
0
22
0
% D
% Glu:
8
22
8
0
8
0
15
22
22
22
0
22
8
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
15
8
8
8
8
0
8
0
8
8
8
0
0
0
0
% G
% His:
8
15
8
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
8
% I
% Lys:
15
8
0
8
0
15
0
0
8
15
0
8
8
8
15
% K
% Leu:
15
0
0
8
15
8
0
15
0
8
0
15
29
15
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
15
0
8
8
0
0
0
8
15
0
0
22
% N
% Pro:
15
8
15
0
22
22
15
15
0
0
15
15
8
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
8
0
8
0
0
8
15
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
15
43
29
15
22
8
22
8
22
22
15
0
15
% S
% Thr:
0
15
8
0
8
0
0
8
15
15
15
0
0
8
0
% T
% Val:
15
8
0
0
0
8
0
8
8
15
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _